Herbert  Waldmann
Herbert Waldmann
Max-Planck-Institut Dortmund
Bestätigte E-Mail-Adresse bei
Zitiert von
Zitiert von
An acylation cycle regulates localization and activity of palmitoylated Ras isoforms
O Rocks, A Peyker, M Kahms, PJ Verveer, C Koerner, M Lumbierres, ...
Science 307 (5716), 1746-1752, 2005
Fluorogenic probes for live-cell imaging of the cytoskeleton
G Lukinavičius, L Reymond, E D'este, A Masharina, F Göttfert, H Ta, ...
Nature methods 11 (7), 731-733, 2014
Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation
A Hakkim, TA Fuchs, NE Martinez, S Hess, H Prinz, A Zychlinsky, ...
Nature chemical biology 7 (2), 75-77, 2011
The Pictet–Spengler reaction in nature and in organic chemistry
J Stöckigt, AP Antonchick, F Wu, H Waldmann
Angewandte Chemie International Edition 50 (37), 8538-8564, 2011
Chemical strategies for generating protein biochips
P Jonkheijm, D Weinrich, H Schröder, CM Niemeyer, H Waldmann
Angewandte Chemie International Edition 47 (50), 9618-9647, 2008
From protein domains to drug candidates—natural products as guiding principles in the design and synthesis of compound libraries
R Breinbauer, IR Vetter, H Waldmann
Angewandte Chemie International Edition 41 (16), 2878-2890, 2002
Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling
G Zimmermann, B Papke, S Ismail, N Vartak, A Chandra, M Hoffmann, ...
Nature 497 (7451), 638-642, 2013
Charting biologically relevant chemical space: a structural classification of natural products (SCONP)
MA Koch, A Schuffenhauer, M Scheck, S Wetzel, M Casaulta, A Odermatt, ...
Proceedings of the National Academy of Sciences 102 (48), 17272-17277, 2005
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis
G Siegel, G Obernosterer, R Fiore, M Oehmen, S Bicker, M Christensen, ...
Nature cell biology 11 (6), 705-716, 2009
Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products
AP Antonchick, C Gerding-Reimers, M Catarinella, M Schürmann, H Preut, ...
Nature chemistry 2 (9), 735-740, 2010
Biology‐oriented synthesis
S Wetzel, RS Bon, K Kumar, H Waldmann
Angewandte Chemie International Edition 50 (46), 10800-10826, 2011
Target identification for small bioactive molecules: finding the needle in the haystack
S Ziegler, V Pries, C Hedberg, H Waldmann
Angewandte Chemie International Edition 52 (10), 2744-2792, 2013
Inhibitors of protein tyrosine phosphatases: Next‐generation drugs?
L Bialy, H Waldmann
Angewandte Chemie International Edition 44 (25), 3814-3839, 2005
The palmitoylation machinery is a spatially organizing system for peripheral membrane proteins
O Rocks, M Gerauer, N Vartak, S Koch, ZP Huang, M Pechlivanis, ...
Cell 141 (3), 458-471, 2010
Protecting group strategies in organic synthesis
M Schelhaas, H Waldmann
Angewandte Chemie International Edition in English 35 (18), 2056-2083, 1996
Catalytic enantioselective 1, 3-dipolar cycloadditions of azomethine ylides for biology-oriented synthesis
R Narayan, M Potowski, ZJ Jia, AP Antonchick, H Waldmann
Accounts of Chemical Research 47 (4), 1296-1310, 2014
Charting, navigating, and populating natural product chemical space for drug discovery
H Lachance, S Wetzel, K Kumar, H Waldmann
Journal of medicinal chemistry 55 (13), 5989-6001, 2012
Small-molecule inhibition of APT1 affects Ras localization and signaling
FJ Dekker, O Rocks, N Vartak, S Menninger, C Hedberg, R Balamurugan, ...
Nature chemical biology 6 (6), 449-456, 2010
The scaffold tree− visualization of the scaffold universe by hierarchical scaffold classification
A Schuffenhauer, P Ertl, S Roggo, S Wetzel, MA Koch, H Waldmann
Journal of chemical information and modeling 47 (1), 47-58, 2007
New modalities for challenging targets in drug discovery
E Valeur, SM Guéret, H Adihou, R Gopalakrishnan, M Lemurell, ...
Angewandte Chemie International Edition 56 (35), 10294-10323, 2017
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